Clinical Trial

Individualized Non-invasive Brain Stimulation for the Treatment of Major Depressive Disorder

Study acronym: CL-tACS RCT
Active, Not Recruiting
View on ClinicalTrials.gov →
Record status
This record was last updated May 15, 2026 (before its estimated May 22, 2026 completion). Its status may not reflect the trial's current state.
Summary
The purpose of this research study is to study a closed-loop transcranial alternating current stimulation (tACS) device to evaluate feasibility of the product in a clinical trial and collect preliminary data on potential effects on symptoms of depression in people with major depressive disorder.
Protocol Amendment History 2 amendments
This ClinicalTrials.gov record has been amended 2 times since 2025-03-11; most recent amendment 2026-05-12.
Status change: Recruiting → Active, Not Recruiting 2026-05-12
Status change: Not Yet Recruiting → Recruiting 2025-04-11
Trial Details
NCT Number NCT06874374
Lead Sponsor Pulvinar Neuro, LLC
Collaborators: National Institute of Mental Health (NIMH), University of North Carolina, Chapel Hill
Conditions Depression - Major Depressive Disorder, Transcranial Alternating Current Stimulation
Enrollment 40 participants
Start Date 2025-04-11
Primary Completion 2026-05-22 (estimated)
Study Completion 2026-06-22 (estimated)
Updated on ClinicalTrials.gov 2026-05-15