Ocular Complications From Cancer Therapy - Patient Registry and Biobank

The purpose of this study is to collect data on patients seen at University of Maryland after undergoing cancer therapy. Previous medications, ocular history, medical history, clinical evaluations, surgical procedures and outcomes will be gathered on the patients who consent to participate. Potential subjects will be enrolled from the clinical practice of the investigator at the time of their eye examination visit. A standard of care exam will be performed pertinent to the reason for the visit. In addition to the standard of care exam, certain biological specimens (ocular surface wash, mucocellular material, corneal filaments, impression cytology, and/or blood) will be collected, stored, and analyzed to obtain immunologic, cellular, or molecular mechanistic insights into disease pathogenesis.

NCT Number	NCT06874283
Lead Sponsor	University of Maryland, Baltimore
Conditions	Graft Versus Host Disease in Eye, Ocular Complications, Inflammatory Dry Eye Disease
Enrollment	150 participants
Start Date	2025-05-13
Primary Completion	2031-04 (estimated)
Study Completion	2031-04 (estimated)
Updated on ClinicalTrials.gov	2026-03-05