Clinical Trial

Social Cognition in Dystrophinopathies and Neurodevelopmental Disorders

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Summary
The primary aim of this observational study is to investigate specific aspects of social cognition in dystrophinopathies. Body awareness, interpersonal distance and emotional processing will be measured in a sample of patients affected by Becker (BMD) and Duchenne (DMD) muscular dystrophy, compared with a sample of patients affected by osteogenesis imperfecta (OI), and both compared with a control sample with typical development. The secondary aim is to study cortical activity at rest, by means of electroencephalography (EEG), to explore frequencies and time course of EEG responses. Moreover, the relationship between EEG activity and neuropsychological, dispositional and subjective measures will be explored through correlational analyses.
Trial Details
NCT Number NCT06874166
Lead Sponsor IRCCS Eugenio Medea
Conditions Duchenne / Becker Muscular Dystrophy, Osteogenesis Imperfecta (OI), Social Cognition
Enrollment 45 participants
Start Date 2025-09
Primary Completion 2027-09 (estimated)
Study Completion 2027-12 (estimated)
Updated on ClinicalTrials.gov 2025-03-13