Reducing Pneumonia with LMA in Lung Wedge Resection

This retrospective cohort study aims to evaluate whether spontaneous breathing laryngeal mask anesthesia (LMA-SBA) reduces the incidence of postoperative pneumonia compared to single-lung isolation mechanical ventilation in patients undergoing thoracoscopic wedge resection. Using propensity score overlap weighting, we will adjust for multiple confounders, including age, COPD, surgical duration, and preoperative laboratory values. Secondary outcomes include postoperative recovery time, fever severity, white blood cell count, neutrophil percentage, length of hospital stay, and ICU admission rate. The study has been approved by the Ethics Committee of the First Affiliated Hospital of Shandong First Medical University (Approval No. YXLL-KY-2025(037)).

NCT Number	NCT06873958
Lead Sponsor	Hai Feng
Conditions	Pneumonia, Postoperative, Anesthesia, Thoracic Surgery, Thoracoscopic Wedge Resection
Enrollment	700 participants
Start Date	2025-03-15
Primary Completion	2025-03-30 (estimated)
Study Completion	2025-04-30 (estimated)
Updated on ClinicalTrials.gov	2025-03-13