Research of Predictive Factors of in Vitro Fertilization (IVF) Outcome AI-IVF Study

Infertility is the failure to achieve a clinical pregnancy after 12 months or more of regular unprotected intercourse, while subfertility means a delay in achieving pregnancy. Several factors can contribute to these conditions, such as autoimmune diseases like systemic thyroid and celiac diseases, rheumatoid arthritis, systemic lupus erythematosus, and endometriosis. Some of them may overlap, sharing a common immunological milieu. In this scenario, medically ART can help women carry on pregnancies if they are in stable disease remission and receive adequate treatment. However, the number of oocytes that can be ovulated under stimulation is highly variable, so the outcome of any IVF is linked to many factors, not only biological but also connected to the mean success rate of the fertility center. For these reasons, the need to find methods for identifying the best gametes and embryos to guarantee a successful pregnancy is becoming pressing. AI can be essential to develop prediction models for pregnancy outcomes for patients undergoing ART treatments. AI currently represents a modern way to obtain algorithms from a set of observable data that could help clinical decisions

NCT Number	NCT06872294
Lead Sponsor	Fondazione IRCCS Policlinico San Matteo di Pavia Collaborators: University of Pavia
Conditions	Autoimmune Diseases
Enrollment	200 participants
Start Date	2024-11-22
Primary Completion	2025-12 (estimated)
Study Completion	2025-12 (estimated)
Updated on ClinicalTrials.gov	2025-03-20