Thoraco Lumbar Vertebral Length and Bupivacaine Dosage in C-Section

Our hypothesis is that the bupivacaine dose determined according to the thoracolumbar vertebral body length (VBL) is more effective in achieving a lower hypotension rate during spinal anesthesia for cesarean delivery than the dose usually adjusted based on height and weight. The VBL measurements were determined from the midpoint of C7 to the tuffier line L4 spinous process. Method: Patients ranging in height from 150 to 170 were randomly assigned to either Group 1 (0.2 mg of 0.5% hyperbaric bupivacaine per cm VBL or Group 2 (height-adjusted dose of 0.5% hyperbaric bupivacaine based on a minimum dose of 0.065 mg/cm according to height) or Group 3 (height-adjusted dose of 0.5% hyperbaric bupivacaine based on a minimum height-adjusted dose of 0.065 mg/cm).

NCT Number	NCT06869434
Lead Sponsor	TC Erciyes University
Conditions	Obstetric Anesthesia Problems, Bupivacaine Adverse Reaction
Enrollment	446 participants
Start Date	2025-05-20
Primary Completion	2025-12-01 (estimated)
Study Completion	2025-12-15 (estimated)
Updated on ClinicalTrials.gov	2026-04-24