Clinical Trial

Bronchoscopic Microwave Ablation of Lung Tissue in Surgical Candidates - UK

Study acronym: AB1MALTISC-UK
Recruiting
View on ClinicalTrials.gov →
Summary
This study involves the use of a medical device, the Creo Medical MicroBlate Flex instrument, to heat and destroy lung tumour cells using microwave energy (this is also called ablation). In this study, the investigators are investigating whether the ablation instrument can be used effectively to treat lung tumours or tumours that have spread to the lungs. If successful, using this technology may mean future patients may not need to undergo surgical removal of these types of lung tumours. The aim of this study is to evaluate the safety and performance of the MicroBlate Flex instrument in treating individuals with cancerous lung tumours that are due to be removed by surgery. All participants in the study will undergo the microwave ablation procedure, which is a separate and additional procedure to their surgical procedure. The study, funded by Creo Medical, will be conducted at sites in the UK and Italy, and will involve up to 18 participants.
Protocol Amendment History 2 amendments
This ClinicalTrials.gov record has been amended 2 times since 2025-03-05; most recent amendment 2026-04-16.
Status change: Not Yet Recruiting → Recruiting 2025-09-19
Trial Details
NCT Number NCT06869122
Lead Sponsor Creo Medical Limited
Conditions Lung Cancer
Enrollment 18 participants
Start Date 2025-07-14
Primary Completion 2026-11 (estimated)
Study Completion 2026-12 (estimated)
Updated on ClinicalTrials.gov 2026-04-21