Predict CHimio-or Radiation-induced NAusea and Vomiting in Children/adolescents Treated for Cancer

Chemo- or radiation-induced nausea and vomiting (CRVN) is one of the most frequent and feared side effects. It is a symptom that is few or not at all evaluated. There is a significant discrepancy between the perception of the CRVN symptom by caregivers and the patient's own experience. At present, there is no real consensus to manage CRVN with medication, and CRVN relief is also the subject of heterogeneous practices. The importance of primary prevention of CRVN, before starting the first treatment sequence, has been highlighted to optimize the action of antiemetic treatments and limit the risk of anticipated nausea and vomiting (NV). The investigators' objective is to objectively assess the risk of CRVN in children/adolescents treated for cancer (and thus effectively prevent this symptom).

NCT Number	NCT06869005
Lead Sponsor	Rennes University Hospital
Conditions	Childhood Cancer, Nausea with Vomiting Chemotherapy-Induced
Enrollment	150 participants
Start Date	2025-03
Primary Completion	2026-05 (estimated)
Study Completion	2026-07 (estimated)
Updated on ClinicalTrials.gov	2025-03-11