Evaluation of the Effectiveness of Different Procedures on Palatinal Wound Healing After Free Gingival Graft Surgery.

This study aimed to help determine the appropriate method to accelerate wound healing at the free gingival graft donor site and to minimize the patient's postoperative complaints. For this purpose, gelatin sponge impregnated with injectable platelet-rich fibrin (I-PRF), gelatin sponge impregnated with 0.8% polyvinylpyrrolidone sodium hyaluronate (HA) gel, and standard gelatin sponge application were compared to the secondary wound site on the palate. The main questions aimed at being answered are: * Does the use of I-PRF or HA accelerate wound healing in patients? * Does the use of I-PRF or HA reduce pain and burning symptoms? * For this purpose, gelatin sponge impregnated with injectable platelet-rich fibrin (I-PRF), gelatin sponge impregnated with 0.8% polyvinylpyrrolidone sodium hyaluronate (HA) gel, and standard gelatin sponge application were compared to the secondary wound site on the palate. Participants will: * They will record whether there is pain and burning for 7 days after the operation. * They will record if there is bleeding in the palate area. * They will write the number of painkillers they use daily. * They will visit the clinic on the 3rd, 5th, 7th, 14th, 21st, 28th days and 1st and 3rd months after the operation.

NCT Number	NCT06867055
Lead Sponsor	SEVAL CEYLAN ŞEN Collaborators: İNCİ PHARMA
Conditions	Insufficient Keratinized Gingiva
Enrollment	67 participants
Start Date	2023-05-15
Primary Completion	2025-08-15 (estimated)
Study Completion	2025-09-15 (estimated)
Updated on ClinicalTrials.gov	2026-03-04