Collaborative Research: Multiscale Modeling and Intervention for Improving Long-Term Medication

The goal of this study is to learn about the impact of an integrated medication monitoring system in breast cancer survivors aged 21-70 who are prescribed endocrine therapy. The main question it aims to address is: Does the integrated medication monitoring system improve medication adherence among breast cancer survivors when used over a six-month period? Fifteen English-speaking breast cancer survivors who meet the inclusion criteria will use a combination of smartphone-based ecological momentary assessments, a medication event monitoring system (Wisepill), and a wearable sensor (Fitbit). After 2 months, participants will be provided personalized content to facilitate medication adherence through an app (Digital Trails) and through WisePill. Participants will complete online surveys at baseline, 3 months, and 6 months to assess their experiences and adherence.

NCT Number	NCT06865755
Lead Sponsor	San Diego State University Collaborators: University of Virginia, National Cancer Institute (NCI)
Conditions	Breast Cancer Survivor, Breast Cancer Early Stage Breast Cancer (Stage 1-3)
Enrollment	15 participants
Start Date	2026-07
Primary Completion	2026-12 (estimated)
Study Completion	2026-12 (estimated)
Updated on ClinicalTrials.gov	2026-04-27