Clinical Trial

53-Week Study Evaluating the Safety and Efficacy of Intra-articular Injections of TPX-100 With Mild to Severe Tibio-Femoral Osteoarthritis of the Knee

Active, Not Recruiting Phase 2
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Summary
53-Week Study Evaluating the Safety and Efficacy of Intra-articular (IA) Injections of TPX-100 vs Placebo in Subjects with Mild to Severe Tibio-Femoral Osteoarthritis of the Knee
Protocol Amendment History 14 amendments
This ClinicalTrials.gov record has been amended 14 times since 2025-03-03; most recent amendment 2026-02-13.
Status change: Recruiting → Active, Not Recruiting 2026-02-13
Status change: Not Yet Recruiting → Recruiting 2025-05-01
Trial Details
NCT Number NCT06865079
Lead Sponsor OrthoTrophix, Inc
Conditions Osteoarthritis (OA) of the Knee
Enrollment 270 participants
Start Date 2025-05-09
Primary Completion 2027-03-25 (estimated)
Study Completion 2027-04-15 (estimated)
Updated on ClinicalTrials.gov 2026-02-17