Clinical Trial

Efficacy and Safety of Celecoxib/Acetaminophen Versus Celecoxib for Diagnosed Osteoarthritis in Acute Exacerbation

Study acronym: PRECEDENT
Recruiting Phase 3
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Record status
This record was last updated April 4, 2025 (before its estimated October 30, 2025 completion). Its status may not reflect the trial's current state.
Summary
This is a Phase III, longitudinal, multicenter, randomized, double-blind clinical trial designed to evaluate the efficacy and safety of a fixed-dose combination of celecoxib and acetaminophen compared to celecoxib monotherapy for the treatment of pain associated with acute exacerbations of osteoarthritis.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2025-03-06.
Trial Details
NCT Number NCT06863636
Lead Sponsor Laboratorios Silanes S.A. de C.V.
Conditions Joint Pain, Knee Osteoarthritis, Hip Osteoarthritis
Enrollment 231 participants
Start Date 2024-09-09
Primary Completion 2025-10-30 (estimated)
Study Completion 2025-11-30 (estimated)
Updated on ClinicalTrials.gov 2025-04-04