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Comparison of Denervation Techniques for the Treatment of Knee Osteoarthritis: Continuous Ablative Radiofrequency Vs. Chemical Denervation with Absolute Alcohol

StatusNot Yet Recruiting
PhaseNot applicable
Started
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Record status
This record was last updated March 11, 2025 (before its estimated September 2026 completion). Its status may not reflect the trial's current state.

Record History

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  1. Minor Study title shortened, about 5 wordsv2
  2. Minor Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
This randomized clinical trial compares two minimally invasive treatments for knee osteoarthritis pain that has not responded to conventional therapies. The study evaluates the effectiveness and safety of continuous ablative radiofrequency, which uses heat energy to disrupt pain signals, and chemical denervation with absolute alcohol, which involves an injection to reduce pain transmission. Participants will be randomly assigned to one of the treatments, and their pain levels, mobility, and quality of life will be monitored over time to determine which method provides better pain relief.
Trial Details
NCT Number NCT06858228
Lead Sponsor Federal University of São Paulo
Conditions
(from sponsor)
Osteoarthritis Knee, Chronic Pain
Related terms Chronic Pain, Osteoarthritis, Knee
Enrollment 288 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov