NoPro - Norwegian Hernia Prophylaxis Study

A multicenter randomized controlled trial comparing midline laparotomy closures using the small-bite suture technique alone to those using the small-bite suture technique with an additional onlay prophylactic polypropylene mesh. The primary endpoint is the incidence of incisional hernias in both groups after one year.

NCT Number	NCT06858020
Lead Sponsor	Sykehuset Innlandet HF
Conditions	Incisional Hernia After Midline Laparotomy, Quality of Life (QOL), Burst Abdomen, Surgical Site Infections
Enrollment	150 participants
Start Date	2025-02-17
Primary Completion	2028-12 (estimated)
Study Completion	2028-12 (estimated)
Updated on ClinicalTrials.gov	2025-03-05