Prevention Ambassadors: Intervention to Promote HIV Service Engagement in the Networks of SSP Clients

HIV testing and service uptake are infrequent among people who use drugs (PWUD) in the United States. In partnership with a community-based syringe service program (SSP), this project will develop the SSP-based "Prevention Ambassadors" (PA) intervention to promote HIV testing and service uptake among PWUD via the secondary distribution (i.e., peer delivery) of HIV self-testing (HIVST) kits with local HIV service information and referrals to HIV service navigation in the social networks of SSP clients (i.e., PWUD). The PA intervention will then be piloted to assess its preliminary effects, acceptability, and feasibility among PWUD in the Ending the HIV Epidemic priority jurisdiction of Riverside County, California.

NCT Number	NCT06848686
Lead Sponsor	San Diego State University Collaborators: University of California, San Diego, University of California, Riverside, Dap Health, National Institute on Drug Abuse (NIDA)
Conditions	HIV
Enrollment	210 participants
Start Date	2025-02-03
Primary Completion	2026-07 (estimated)
Study Completion	2027-02 (estimated)
Updated on ClinicalTrials.gov	2026-01-29