Oral Metformin for Treating Melasma in Latin American Women

The goal of this clinical trial is to learn if metformin can treat melasma in Latin American women. The main question it aims to answer is: \- Can metformin help reduce the dark patches of melasma? Researchers will test two different doses of metformin (500 mg and 1000 mg) to see if either one helps improve melasma. Participants will: * Take a metformin pill every day for three months. * Go to the clinic twice: once at the beginning and once at the end of the study. * Get a phone call from the researchers to check how they're doing and ask about any changes or side effects.

NCT Number	NCT06845540
Lead Sponsor	University of Puerto Rico
Conditions	Melasma
Enrollment	30 participants
Start Date	2025-02-20
Primary Completion	2025-05-22 (estimated)
Study Completion	2025-05-30 (estimated)
Updated on ClinicalTrials.gov	2025-02-25