AO CSH Mainstream Study on Cervical Spine Degeneration

Adult patients with cervical degenerative diseases undergoing primary anterior and/or posterior cervical fusion will be prospectively enrolled from participating sites. Patients will be treated and followed up at the participating sites per local standard of care. Several variables related to the patient characteristics and fusion details will be collected. The mainstream study will not collect follow-up (FU) data. The duration of this patient cohort is currently planned as open ended.

NCT Number	NCT06845293
Lead Sponsor	AO Innovation Translation Center
Conditions	Cervical Spine Degenerative Disease
Enrollment	300 participants
Start Date	2025-07-01
Primary Completion	2030-07-31 (estimated)
Study Completion	2035-07-31 (estimated)
Updated on ClinicalTrials.gov	2025-02-25