Clinical Trial

The International Spinal Cord Injury Blood Biomarker Longitudinal Evaluation (I-SCRIBBLE) Study

Recruiting
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Summary
To determine the accuracy of serum NF-L and GFAP levels (ie the biomarkers) at different time points postinjury for predicting the severity of neurologic impairment at 6 months postinjury as either motor complete (AIS grade A/B) or motor incomplete (AIS grade C/D) a group of patients who suffer traumatic spinal fracture and/or dislocation of the spinal column but without neurologic injury will be enrolled as non-SCI spine trauma control participants.
Protocol Amendment History 3 amendments
This ClinicalTrials.gov record has been amended 3 times since 2025-02-17; most recent amendment 2026-05-04.
Status change: Not Yet Recruiting → Recruiting 2026-03-02
Trial Details
NCT Number NCT06839300
Lead Sponsor AO Foundation, AO Spine
Conditions Spinal Cord Injury
Enrollment 260 participants
Start Date 2026-02-09
Primary Completion 2029-12-01 (estimated)
Study Completion 2029-12-01 (estimated)
Updated on ClinicalTrials.gov 2026-05-05