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Effects of Vibrating Mesh Nebulisation in Patients on Long-term Tracheostomy Ventilation: a Pilot Randomised Crossover Trial

Study acronym: EVOLVE
StatusActive, Not Recruiting
PhaseNot applicable
Started
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Record History

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  1. Trial status: Not Yet Recruiting to Active, Not Recruitingv3 Show 4 more changesShow less
    • Primary completion date changed from estimate of May 1, 2026 to Sep 10, 2025
    • Study completion date: May 1, 2026 to Dec 1, 2026
    • Start date changed from estimate of Mar 1, 2025 to Mar 20, 2025
    • Site details revised
  2. Secondary endpoints revised (8)v2
  3. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
Assessment of the effects of vibrating mesh nebulisation versus jet nebulisation on respiratory function in patients with long-term tracheostomy ventilation: evaluating neural respiratory drive, breathing mechanics, cardiac parameters, secretions, and breathlessness
Trial Details
NCT Number NCT06834581
Lead Sponsor Guy's and St Thomas' NHS Foundation Trust
Conditions
(from sponsor)		 Long-term Tracheostomy Ventilated Patients
Enrollment 12 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov