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A Study of Brentuximab Vedotin With Doxorubicin, Vinblastine and Dacarbazine in Adults With Hodgkin Lymphoma in India

StatusRecruiting
PhasePhase 4
SponsorTakeda
Started2024-08-28
View on ClinicalTrials.gov ↗
The main aim of this study is to check how safe brentuximab vedotin is in adults with untreated Hodgkin Lymphoma (HL) when given together with doxorubicin (Adriamycin), vinblastine and dacarbazine therapy ('AVD'). Another aim is to learn how well treatment of brentuximab vedotin plus AVD works. All participants will receive brentuximab vedotin plus AVD for approximately 6 months. Participants will undergo tests like Echocardiography (ECHO) and pulmonary function testing (PFT) during the study. ECHO is a test that uses ultrasound to show how the heart muscle and valves are working; PFT is a test to check how well a participant's lungs work. Each participant will undergo a final health status check 2 months after the last treatment with brentuximab vedotin plus AVD.

Amendment record

Amended 2 times since 2025-02-14; most recent filed 2026-02-19. Every amendment is listed below.

Dates here are the day the sponsor filed the amendment, not the day ClinicalTrials.gov published it. Version history last read from ClinicalTrials.gov on 2026-08-30.

2026-02-19
Amendment Study Status, References v2
2026-02-05
Amendment Study Status, Contacts/Locations, References v1
2025-02-14
Original filing
Trial Details
NCT Number NCT06831370
Lead Sponsor Takeda
Conditions Hodgkin Lymphoma
Enrollment 124 participants
Start Date 2024-08-28
Primary Completion 2028-03-31 (estimated)
Study Completion 2028-03-31 (estimated)
Updated on ClinicalTrials.gov 2026-02-23