Evaluating Q-Collar Effects on Brain Blood Flow Control During Exercise

The goal of this clinical trial is to learn how the FDA-cleared Q-Collar device affects brain blood flow regulation during rest and exercise in healthy adults. The main questions this study aims to answer are: 1. How does the Q-Collar affect brain blood flow when there are quick changes in blood pressure, like when standing up quickly, or when breathing against resistance? 2. How does the Q-Collar affect brain blood flow during exercise? Researchers will compare sessions where participants wear the Q-Collar to sessions where they do not wear the device to see if the Q-Collar improves brain blood flow during both rest and exercise. Participants will: * Complete two study visits, each 1 to 4 weeks apart. * Perform a series of tasks, including standing tests, breathing tests, and exercise on a stationary bike, while their heart rate, brain blood flow, and other body functions are monitored. * Wear the Q-Collar during one of the sessions and not wear it during the other session. The order of the sessions will be randomly assigned.

NCT Number	NCT06826781
Lead Sponsor	Spaulding Rehabilitation Hospital
Conditions	Healthy
Enrollment	20 participants
Start Date	2025-07-23
Primary Completion	2026-07-23 (estimated)
Study Completion	2026-08-23 (estimated)
Updated on ClinicalTrials.gov	2025-10-27