Clinical Trial

Delay AvoIding Primary Evaluation for ThRombectomy of Acute StrokE Patients With Large Vessel OCclusion in the Angiography SuiTe

Study acronym: DIRECT
Recruiting
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Summary
The purpose of this study is to compare two strategies for treating adults with suspected large vessel occlusion stroke within 7 hours of symptom onset. Researchers will evaluate whether direct transfer to the neurointerventional angiography suite improves recovery and reduces disability compared to the conventional approach of first being evaluated in the emergency department. The study will also assess safety and other health outcomes to guide care for stroke patients.
Protocol Amendment History 3 amendments
This ClinicalTrials.gov record has been amended 3 times since 2025-02-09; most recent amendment 2026-03-11.
Status change: Not Yet Recruiting → Recruiting 2026-03-11
Trial Details
NCT Number NCT06825897
Lead Sponsor Santiago Ortega Gutierrez
Collaborators: Patient-Centered Outcomes Research Institute
Conditions Stroke, Acute
Enrollment 2,039 participants
Start Date 2026-01-27
Primary Completion 2028-04-30 (estimated)
Study Completion 2028-04-30 (estimated)
Updated on ClinicalTrials.gov 2026-03-13