Investigating the Impacts of Early Life Experience on the Brain & Behaviour

The aim of this study is to learn more about how early life experience influences the brain, behaviour, and the immune system later in life. This will help improve understanding of why certain early life experiences (e.g., adoption, stress and parental separation) can cause difficulties for some people when they are adults. The long-term goal of this research is to develop tools that could identify young people who are vulnerable to developing future problems, this will ensure people get the help that they need at the right time for them. This study will use psychological assessment, online games, brain imaging and blood sampling to help improve our understanding of how and why early life experience can influence mental health, cognition, brain development and the immune system later in life.

NCT Number	NCT06823492
Lead Sponsor	University of Manchester
Conditions	Mental Health, Neurodevelopment, ADHD, Autism, Depression - Major Depressive Disorder, Anxiety Disorder (Panic Disorder or GAD)
Enrollment	120 participants
Start Date	2023-04-01
Primary Completion	2025-12-30 (estimated)
Study Completion	2027-12-30 (estimated)
Updated on ClinicalTrials.gov	2025-02-12