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DDR Genes Alteration and Response to Platinum-based Chemotherapy in Advanced Urothelial Cancer.

Study acronym: SELECTIO-UC
StatusRecruiting
PhasePhase 4
Started
View on ClinicalTrials.gov ↗
Record status
This record was last updated February 11, 2025 (before its estimated January 7, 2026 completion). Its status may not reflect the trial's current state.

Record History

  1. Study First Submitted
This study aims to prospectively observe whether certain alterations in some genes related to the DNA repair mechanism are related to better response to platinum-based chemotherapy used to treat metastatic bladder or urothelial cancers.
Trial Details
NCT Number NCT06820255
Lead Sponsor Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Conditions
(from sponsor)		 Bladder (Urothelial, Transitional Cell) Cancer Metastatic or Unresectable, Upper Tract Urothelial Cancer
Related terms Neoplasm Metastasis
Enrollment 135 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov