Clinical Trial

DDR Genes Alteration and Response to Platinum-based Chemotherapy in Advanced Urothelial Cancer.

Study acronym: SELECTIO-UC
Recruiting Phase 4
View on ClinicalTrials.gov →
Record status
This record was last updated February 11, 2025 (before its estimated January 7, 2026 completion). Its status may not reflect the trial's current state.
Summary
This study aims to prospectively observe whether certain alterations in some genes related to the DNA repair mechanism are related to better response to platinum-based chemotherapy used to treat metastatic bladder or urothelial cancers.
Trial Details
NCT Number NCT06820255
Lead Sponsor Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Conditions Bladder (Urothelial, Transitional Cell) Cancer Metastatic or Unresectable, Upper Tract Urothelial Cancer
Enrollment 135 participants
Start Date 2025-01-07
Primary Completion 2026-01-07 (estimated)
Study Completion 2027-01-07 (estimated)
Updated on ClinicalTrials.gov 2025-02-11