A Study to Prevent Infantile Spasms Relapse

After initially successful treatment, many children with infantile spasms unfortunately have a relapse, and relapse is linked to poor long-term outcomes such as autism and other forms of epilepsy. The aim of this study is to determine if treatment with low-dose prednisolone is safe, well tolerated, and effective in reducing the risk of relapse.

NCT Number	NCT06819670
Lead Sponsor	University of California, Los Angeles Collaborators: Pediatric Epilepsy Research Foundation
Conditions	Infantile Spasms, Infantile Epileptic Spasms Syndrome, West Syndrome
Enrollment	40 participants
Start Date	2025-05-05
Primary Completion	2028-02-28 (estimated)
Study Completion	2028-06-30 (estimated)
Updated on ClinicalTrials.gov	2025-05-08