Clinical Trial

Comparison of Outcomes of Management of Bowel Obstruction Pilot Study

Study acronym: COMBO Pilot
Enrolling by Invitation Phase 4
View on ClinicalTrials.gov →
Record status
This record was last updated March 12, 2025 (before its estimated December 2025 completion). Its status may not reflect the trial's current state.
Summary
The Comparison of Outcomes of Management of Bowel Obstruction (COMBO Pilot) Pilot trial is a patient-level randomized trial of a short course of dexamethasone + supportive care vs supportive care alone for patients with adhesion-related small bowel obstruction (aSBO). The goal of the COMBO trial is to answer the question: Can Dexamethasone increases the proportion of patients with resolution of aSBO with non-operative management (without complication) based on an established minimal important clinical difference.
Protocol Amendment History 2 amendments
This ClinicalTrials.gov record has been amended 2 times since 2025-02-04; most recent amendment 2026-02-20.
Status change: Enrolling by Invitation → Completed 2026-02-20
Status change: Not Yet Recruiting → Enrolling by Invitation 2025-03-07
Trial Details
NCT Number NCT06817551
Lead Sponsor University of Washington
Conditions Adhesive Small Bowel Obstruction
Enrollment 10 participants
Start Date 2025-03-01
Primary Completion 2025-12 (estimated)
Study Completion 2026-03 (estimated)
Updated on ClinicalTrials.gov 2025-03-12