Multi-strain Probiotics to Prevent Necrotizing Enterocolitis in Very Preterm Infants

The goal of this clinical trial is to evaluate whether multi-strain probiotics of lactobacillus and bifidobacterium can prevent necrotizing enterocolitis (NEC) in preterm infants born at less than 32 weeks of gestation. The main questions it aims to answer are: * Does the use of a multi-strain probiotic combination reduce the incidence of NEC in preterm infants? * Are there any adverse effects associated with the administration of this probiotic combination?

NCT Number	NCT06810154
Lead Sponsor	University of Calgary
Conditions	Necrotizing Enterocolitis (NEC)
Enrollment	2,170 participants
Start Date	2025-06-01
Primary Completion	2027-05-30 (estimated)
Study Completion	2028-05-30 (estimated)
Updated on ClinicalTrials.gov	2025-02-05