Clinical Trial

COntralateral CorticoSTeroid Injection in Total Knee Arthroplasty

Study acronym: COSTI
Recruiting Phase 1/2
View on ClinicalTrials.gov →
Summary
Through a triple-blinded randomized control trial, the primary purpose of this pilot study is to assess the efficacy of administering peri-operative contralateral corticosteroid injection in patients undergoing TKA. The secondary outcome was to assess the effect of contralateral corticosteroid injection on pain and functional outcomes of patients undergoing TKA.
Protocol Amendment History 2 changes
notable Primary completion pushed: 2026-07-30 -> 2026-08-30 2026-07-14
minor Completion pushed: 2027-07-30 -> 2027-08-30 2026-07-14
Trial Details
NCT Number NCT06809998
Lead Sponsor Unity Health Toronto
Conditions Total Knee Anthroplasty, Osteoarthritis(Primary), Osteoarthritis (OA) of the Knee, Bilateral Knee Osteoarthritis
Enrollment 60 participants
Start Date 2025-01-24
Primary Completion 2026-08-30 (estimated)
Study Completion 2027-08-30 (estimated)
Updated on ClinicalTrials.gov 2026-07-30