Clinical Trial

Sufentanil in Patients With Lower Extremity Fracture Surgery Myocardial Damage Function Study

Study acronym: Sipwlefsmdfs
Not Yet Recruiting
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Record status
This record was last updated February 5, 2025 (before its estimated May 10, 2025 completion). Its status may not reflect the trial's current state.
Summary
1. To analyze the association of different doses of opioids on myocardial injury/protection through BMP-6/SMAD pathway. 2. To observe the effect of different doses of opioids on the expression of BMP-6 in bone marrow. 3. To investigate the relationship between different doses of opioids and BMP-6 and perioperative cardiovascular adverse events in patients with lower extremity fracture surgery.
Trial Details
NCT Number NCT06808841
Lead Sponsor Second Hospital of Shanxi Medical University
Conditions Myocardial Injury
Enrollment 160 participants
Start Date 2025-02-05
Primary Completion 2025-05-10 (estimated)
Study Completion 2025-05-10 (estimated)
Updated on ClinicalTrials.gov 2025-02-05