Study of Hemodynamic Markers of Upper Extremity Motor Dysfunction in Stroke Patients Using Functional Near Infrared Spectroscopy (fNIRS)

The aim of the study was to explore potential pathways for recovery and adaptation of the motor cortex by examining cerebral blood flow characteristics and hemodynamic markers analyzed by functional near-infrared spectroscopy (fNIRS) in patients with hemiparesis after stroke. Participants in the study performed a simple stimulus-response task several times with one healthy and one paralyzed limb at different stages of basic rehabilitation. A group of healthy, age-matched volunteers participated in the same experiment to verify the stroke-related changes. The researchers recorded fNIRS signals, muscle activity using electromyography, and heart activity using electrocardiography.

NCT Number	NCT06806397
Lead Sponsor	Skolkovo Institute of Science and Technology Collaborators: Federal Center of Brain Research and Neurotechnologies of the Federal Medical Biological Agency of Russia
Conditions	Stroke, Stroke with Hemiparesis, Stroke, Ischemic
Enrollment	40 participants
Start Date	2024-06-26
Primary Completion	2025-01-20 (estimated)
Study Completion	2025-04 (estimated)
Updated on ClinicalTrials.gov	2025-02-04