Clinical Trial

Non-invasive Vagus Nerve Stimulation (nVNS) and Cognition in Young Adult Vapers - A Pilot Study

Study acronym: nVNS
Recruiting
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Summary
The purpose of this study is to assess the effects of non-invasive vagus nerve stimulation (nNVS) on cognitive functioning in the users of e-cigarettes or vaping products. The investigators will use a digital wellness companion product (TRUVAGA™ device) that provides mild transcutaneous nVNS. The participants will be randomized to receive either a 2-min nNVS stimulation or control stimulation in the neck region followed by completion of three cognitive tests of attention and executive function.
Protocol Amendment History 4 amendments
This ClinicalTrials.gov record has been amended 4 times since 2025-01-27; most recent amendment 2026-03-05.
Status change: Not Yet Recruiting → Recruiting 2025-03-03
Trial Details
NCT Number NCT06804109
Lead Sponsor Temple University
Conditions Vaping
Enrollment 100 participants
Start Date 2025-03-18
Primary Completion 2027-02-09 (estimated)
Study Completion 2028-02-09 (estimated)
Updated on ClinicalTrials.gov 2026-03-06