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Efficacy and Central Mechanisms of Electroacupuncture for Medication Overuse Headache

StatusRecruiting
PhaseNot applicable
Started
View on ClinicalTrials.gov ↗
Trial flagged as At Risk
Primary completion moved at least 11 months later Dec 2026 → Dec 2027
See other at-risk trials from Guang'anmen Hospital of China Academy of Chinese Medical Sciences

Record History

See every version on ClinicalTrials.gov ↗

  1. Primary completion pushed from Dec 2026 to Dec 2027
    • Study completion pushed from Jun 2027 to Jun 2028
    v5
  2. Trial status: Not Yet Recruiting to Recruiting
    • Start date changed from estimate of Mar 1, 2025 to Feb 1, 2025
    • Site details revised
    v4
  3. Eligibility criteria expanded, about 1 wordv3
  4. Eligibility criteria shortened, about 19 wordsv2
  5. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
Acupuncture is commonly used for the prevention of migraine and tension-type headaches, and has been found to be effective in reducing both the frequency and severity of these conditions. However, studies on acupuncture for medication overuse headache (MOH) are limited, and current research has not been able to determine whether its efficacy is due to the actual therapeutic effects of acupuncture or psychological benefits. To address this issue, the investigators have designed a clinical trial to evaluate the efficacy of acupuncture for MOH. In addition, the investigators will explore the regulatory effects of electroacupuncture on central mechanisms in MOH and conduct multi-omics analysis.
Trial Details
NCT Number NCT06802471
Lead Sponsor Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Conditions
(from sponsor)		 Medication Overuse Headache, Electroacupuncture
Related terms Headache Disorders, Secondary
Enrollment 160 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov