Clinical Trial

A Cohort Study on Biomarkers to Predict the Efficacy of Biologics for Chronic Rhinosinusitis with Nasal Polyps

Not Yet Recruiting Phase 4
View on ClinicalTrials.gov →
Record status
This record was last updated February 6, 2025 (before its estimated December 1, 2025 completion). Its status may not reflect the trial's current state.
Summary
Recently, several biologic therapies have become available for treating chronic rhinosinusitis with nasal polyps (CRSwNP). However, not every patient responds to these treatments. This clinical trial aims to develop a non-invasive predictive model to help determine how effective IL-4Rα targeted monoclonal antibody therapy will be for individuals with CRSwNP.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2025-01-24.
Trial Details
NCT Number NCT06801353
Lead Sponsor Beijing Tongren Hospital
Conditions Chronic Rhinosinusitis with Nasal Polyps (CRSwNP), Biological Therapy, Biomarkers
Enrollment 90 participants
Start Date 2025-02-01
Primary Completion 2025-12-01 (estimated)
Study Completion 2026-07-01 (estimated)
Updated on ClinicalTrials.gov 2025-02-06