Clinical Trial

Efficacy and Safety of Emodepside in Participants With Soil-transmitted Helminth Infections

Study acronym: TREMO-Siargao
Not Yet Recruiting Phase 3
View on ClinicalTrials.gov →
Summary
This study aims to assess the efficacy and safety of emodepside compared to mebendazole in adults and adolescents infected with T. trichiura, either as single infection or co-infections with hookworm and/or A. lumbricoides.
Protocol Amendment History 4 changes
notable Primary completion pushed: 2027-04 -> 2027-06 2026-08-15
minor Completion pushed: 2027-08 -> 2027-10 2026-08-15
notable Primary completion pushed: 2026-09 -> 2027-04 2026-04-30
minor Completion pushed: 2026-12 -> 2027-08 2026-04-30
Trial Details
NCT Number NCT06800248
Lead Sponsor Swiss Tropical & Public Health Institute
Collaborators: Bayer, University of the Philippines, Coefficient Giving (Formerly Open Philanthropy)
Conditions Trichuris Trichiura; Infection, Hookworm Infection, Ascaris Lumbricoides Infection
Enrollment 315 participants
Start Date 2026-11-06
Primary Completion 2027-06 (estimated)
Study Completion 2027-10 (estimated)
Updated on ClinicalTrials.gov 2026-08-14