Train Your Brain Fitness SC: An Exercise Intervention for People With Cognitive Impairments

The goal of this clinical trial is to test a twice a week, moderate intensity exercise and coaching program (an in-person group and a distance group) for adults with mild-moderate cognitive impairments living in South Carolina. The main questions it aims to answer are: 1. Is the program practical to conduct, and it is acceptable and enjoyable? The hypothesis is that it will be possible to recruit participants, obtain the desired dosage of moderate intensity fitness and strength training twice a week for both groups. 2. Are their changes at 3, 6, 9 and 12 months in endurance, mobility, cognitive function and perception of cognitive function? The hypotheses are that endurance, strength and mobility will improve and cognitive measures will not decline (remain the same or improve) for both groups.

NCT Number	NCT06799429
Lead Sponsor	University of South Carolina
Conditions	Mild-moderate Cognitive Impairment
Enrollment	50 participants
Start Date	2026-03-13
Primary Completion	2026-10-31 (estimated)
Study Completion	2026-11-17 (estimated)
Updated on ClinicalTrials.gov	2026-06-01