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Insights Into the Pathophysiology of Neurovascular Uncoupling in Patients With Brain Lesions.

Study acronym: NVUCVR
StatusRecruiting
PhaseNot applicable
Started
View on ClinicalTrials.gov ↗
Trial flagged as At Risk
Primary completion moved at least 3 months later Jun 1, 2026 → Sep 13, 2026
See other at-risk trials from Erasme University Hospital

Record History

  1. Primary completion pushed from Jun 1, 2026 to Sep 13, 2026
    • Study completion pushed from Dec 31, 2026 to Dec 31, 2027
    v3
  2. Trial status: Not Yet Recruiting to Recruiting
    • Study sites: 0 to 1
    • Start date changed from estimate of Feb 10, 2025 to Feb 17, 2025
    v2
  3. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
Erasme University Hospital
31 trials monitored
See 3 trials at risk
Glioma
1,251 trials monitored
See 88 trials at risk
Glioblastoma
710 trials monitored
See 52 trials at risk
Neurovascular uncoupling (NVU) represents a major source of potential bias for the identification of eloquent brain regions through activation procedures in blood oxygen level dependent (BOLD) functional magnetic resonance imaging (fMRI). Same region shows proper pattern in glucose metabolism in victiny of brain lesions, investigated with positron emitted tomography with radiolabeled glucose (PET-FDG) This research project aims at investigating the mechanisms of NVU by using a multimodal noninvasive imaging approach in neurosurgical patients.
Trial Details
NCT Number NCT06797661
Lead Sponsor Erasme University Hospital
Conditions
(from sponsor)		 Glioblastoma, Glioma, Astrocytoma
Related terms Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma
Enrollment 40 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov