Clinical Trial

Insights Into the Pathophysiology of Neurovascular Uncoupling in Patients with Brain Lesions.

Study acronym: NVUCVR
Recruiting
View on ClinicalTrials.gov →
Record status
This record was last updated February 19, 2025 (before its estimated June 1, 2026 completion). Its status may not reflect the trial's current state.
Summary
Neurovascular uncoupling (NVU) represents a major source of potential bias for the identification of eloquent brain regions through activation procedures in blood oxygen level dependent (BOLD) functional magnetic resonance imaging (fMRI). Same region shows proper pattern in glucose metabolism in victiny of brain lesions, investigated with positron emitted tomography with radiolabeled glucose (PET-FDG) This research project aims at investigating the mechanisms of NVU by using a multimodal noninvasive imaging approach in neurosurgical patients.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2025-01-23.
Status change: Not Yet Recruiting → Recruiting 2025-02-17
Trial Details
NCT Number NCT06797661
Lead Sponsor Erasme University Hospital
Conditions Glioblastoma, Glioma, Astrocytoma
Enrollment 40 participants
Start Date 2025-02-17
Primary Completion 2026-06-01 (estimated)
Study Completion 2026-12-31 (estimated)
Updated on ClinicalTrials.gov 2025-02-19