Comparison of RIMA-SVG and Ao-SVG Techniques in Coronary Artery Bypass Grafting

This randomized, double-blind, single-center clinical trial was divided into two groups, RIMA-SVG and Ao-SVG, according to the surgical method. The purpose was to evaluate the effect of the RIMA-SVG surgical method in improving saphenous vein graft (SVG) patency and reducing clinical complications. A total of 300 patients will be enrolled and randomly assigned to two surgical method groups: RIMA-SVG Group (150 patients): SVGs are connected to the right internal mammary artery (RIMA). Ao-SVG Group (150 patients): The aorta is clamped, and SVGs are connected to the ascending aorta (Ao).All patients will undergo CABG on a beating heart with sequential vein grafts to bypass at least two or more coronary vessels. The primary outcome is 1-year graft patency. The secondary outcomes include neurological complications, mortality, major adverse cardiovascular events (MACE), and surgical site infection event.

NCT Number	NCT06787651
Lead Sponsor	Second Hospital of Jilin University
Conditions	Coronary Artery Bypass Grafting, Coronary Artery Disease, Saphenous Vein, Graft Patency
Enrollment	300 participants
Start Date	2025-02-01
Primary Completion	2026-06-01 (estimated)
Study Completion	2026-07-30 (estimated)
Updated on ClinicalTrials.gov	2025-08-06