NutriPlant - Opportunities for Increasing Consumption of Local Fruits and Vegetables

The effects of different foods to normal bowel function in adult population will be investigated. A randomised controlled intervention trial will be conducted on about 120 (30 per group) adult (18-70 years) subjects with functional constipation and irritable bowel syndrome with constipation according to the IV. Rome criteria. At least one week before inclusion in the study, patients will stop taking laxatives and other anti-constipation medications. Subjects will be randomly selected to consume one of the test foods (fresh apples, dried apples, sauerkraut) or the active control (psyllium) in the equivalent amount of 3 g of fiber per day for 4 weeks. Subjects will be asked not to change their lifestyle habits, such as diet and physical activity level, and not to take oral laxatives during the period of participation in the study.

NCT Number	NCT06785831
Lead Sponsor	Institute of Nutrition, Slovenia (Nutris) Collaborators: University Medical Centre Ljubljana, University of Ljubljana
Conditions	Functional Constipation, Irritable Bowel Syndrome
Enrollment	120 participants
Start Date	2025-01-20
Primary Completion	2025-09-01 (estimated)
Study Completion	2026-09-30 (estimated)
Updated on ClinicalTrials.gov	2025-01-21