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Physical Activity and Insulin Sensitivity Dynamics

StatusRecruiting
PhaseNot applicable
Started
View on ClinicalTrials.gov ↗

Record History

  1. Primary completion date changed from estimate of Dec 15, 2026 to Aug 26, 2025v4
  2. Start date: Jan 15, 2025 to May 5, 2025v3
  3. Interventions: Exercise (Other), Exercise (Other), Insulin infusion (Procedure), Muscle Biopsy Medication: Lidocaine (Procedure) to Exercise (Other), Insulin infusion (Procedure), Muscle Biopsy Medication: Lidocaine (Procedure), One-legged-knee extensor exercise (Other)v2
  4. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
The study investigates the role of one single bout of exercise in mediating enhancement of muscle insulin sensitivity following a single bout of exercise. Furthermore, the study is aiming to elucidate the temporal development in insulin signaling, at the early timepoints of insulin stimulation that may be responsible for the enhanced muscle insulin sensitivity. This will be investigated in young healthy males subjected to a one-legged knee-extensor exercise followed by a hyperinsulinemic-euglycemic clamp, a setup known to enhance muscle insulin sensitivity.
Trial Details
NCT Number NCT06776094
Lead Sponsor University of Copenhagen
Conditions
(from sponsor)		 Insulin Sensitivity
Related terms Insulin Resistance, Motor Activity
Enrollment 8 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov