Dietary Supplements to Treat Radiation-Induced Rectal Injury

This clinical study is a prospective, single-arm, single-center trial aimed at assessing the safety and efficacy of tributyrin (TB) as dietary supplements in the treatment of chronic radiation-induced rectal injury (RRI). We hypothesize that these supplements will help improve rectal bleeding symptoms and elevate the quality of life for patients. The study will test whether the supplements can lower the LENT-SOMA scales of rectal bleeding and enhance overall patient health. Efficacy will be evaluated through blood tests and other non-invasive methods, ensuring patient safety and comfort throughout the study.

NCT Number	NCT06776016
Lead Sponsor	Sixth Affiliated Hospital, Sun Yat-sen University
Conditions	Radiotherapy, Radiation Proctitis
Enrollment	33 participants
Start Date	2025-01-15
Primary Completion	2026-09-30 (estimated)
Study Completion	2026-12-31 (estimated)
Updated on ClinicalTrials.gov	2026-08-07