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NCT06773845 · ClinicalTrials.gov record · last posted 2026-08-20

Building Evidence for Ablative Internal Radiation Therapy in Localized HCC Beyond the Up-To-7 Criteria

Study acronym: BEAT-UT7
StatusRecruiting
PhasePhase 2
Started2025-03-11
View on ClinicalTrials.gov ↗
from the ClinicalTrials.gov record
At four major centers in Korea, patients with hepatocellular carcinoma (HCC) that exceed the up-to-7 criteria yet remain locally confined will undergo ablative radioembolization using Yttrium-90 glass microspheres, guided by a standardized dosimetry method. Their treatment response, survival outcomes, and adverse events will be monitored for two years following the procedure.

Protocol amendment history 3 changes detected by DataLookout

2026-08-21
minor
Trial sites expanded: 4 → 8 locations
2026-08-21
critical
Primary completion pushed: 2027-12-31 → 2028-12-31
2026-08-21
minor
Completion pushed: 2029-12-31 → 2030-12-31
Trial Details
NCT Number NCT06773845
Lead Sponsor Seoul National University Hospital
Collaborators: Boston Scientific Corporation
Conditions Hepatocellular Carcinoma (HCC), Radioembolization
Enrollment 100 participants
Start Date 2025-03-11
Primary Completion 2028-12-31 (estimated)
Study Completion 2030-12-31 (estimated)
Updated on ClinicalTrials.gov 2026-08-20