An Exploratory Clinical Study of a Low-dose Buprenorphine Patch for the Treatment of Autism Spectrum Disorders

This study evaluates the safety and efficacy of low-dose buprenorphine in patients with ASD by using standard ASD symptom assessment methods (e.g., SRS-2 and ABC) as well as AI-assisted analyses utilizing exploratory gaze patterns in conjunction with fMRI and electroencephalogram measurements to assess changes in brain functional status.

NCT Number	NCT06772324
Lead Sponsor	Peking University Sixth Hospital Collaborators: Ping An-Shionogi Co., Ltd.
Conditions	Autism Spectrum Disorder
Enrollment	60 participants
Start Date	2025-01
Primary Completion	2026-08 (estimated)
Study Completion	2026-09 (estimated)
Updated on ClinicalTrials.gov	2025-01-13