Investigation of Central Sensitization and Associated Factors in Patients With Lipedema

This study aims to investigate the presence of central sensitization and its associated parameters in patients with lipedema. Lipedema is a chronic and hereditary condition that primarily affects the lower extremities in women and is often associated with hormonal changes. Symptoms such as pain, swelling, and tenderness are common in lipedema, and these symptoms may be related to central sensitization. Additionally, the ultrasonographic findings and pain sensitivity in lipedema will be compared with those of healthy individuals. This study seeks to contribute to the diagnosis and treatment process of lipedema.

NCT Number	NCT06770634
Lead Sponsor	Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Conditions	Lipedema, Central Sensitisation
Enrollment	50 participants
Start Date	2024-12-06
Primary Completion	2025-09-01 (estimated)
Study Completion	2025-12-30 (estimated)
Updated on ClinicalTrials.gov	2025-09-08