Clinical Trial

Optimizing a Remote-based Physical Activity Intervention for Adults With Total Knee Replacement

Study acronym: MOST Energized
Recruiting
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Summary
The purpose of this study is to identify which supplemental intervention components added to an online exercise program contribute to the greatest increases in physical activity (total MVPA and percent meeting guidelines \[≥150 min/week of MVPA\]) in adults with knee replacement at 6 and 12 months. Secondary outcomes will examine changes in pain and physical function.
Protocol Amendment History 3 amendments
This ClinicalTrials.gov record has been amended 3 times since 2025-01-06; most recent amendment 2026-04-28.
Status change: Not Yet Recruiting → Recruiting 2025-01-21
Trial Details
NCT Number NCT06768762
Lead Sponsor University of South Carolina
Collaborators: National Institute on Aging (NIA)
Conditions Knee Replacement
Enrollment 336 participants
Start Date 2025-01-21
Primary Completion 2028-12-30 (estimated)
Study Completion 2029-07-31 (estimated)
Updated on ClinicalTrials.gov 2026-05-05