Clinical Trial

The Role of Epicardial Adiposity in Heart Failure With Preserved Ejection Fraction

Study acronym: EAT HFpEF
Recruiting
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Summary
In this study the investigators are aiming to recruit 130 patients with heart failure with preserved ejection fraction who are obese and non-obese to undergo CT and MRI scans, as well as some other investigations including blood tests, to help investigate if having more fat around the heart leads to worse heart function in this condition. This may lead to the development of new treatments aimed at lowering fat levels around the heart and in the rest of the body, specifically to treat HFpEF.
Protocol Amendment History 2 amendments
This ClinicalTrials.gov record has been amended 2 times since 2025-01-06; most recent amendment 2026-04-29.
Status change: Not Yet Recruiting → Recruiting 2025-03-24
Trial Details
NCT Number NCT06768437
Lead Sponsor University of Leicester
Conditions Heart Failure With Preserved Ejection Fraction (HFPEF)
Enrollment 130 participants
Start Date 2025-02-12
Primary Completion 2027-08 (estimated)
Study Completion 2037-08 (estimated)
Updated on ClinicalTrials.gov 2026-04-30