Exercise-Induced Hypoalgesia Differences Between Upper and Lower Limbs Resistance Training Interventions

This randomized controlled trial with healthy subjects aims to compare exercise-induced hypoalgesia among three groups: one utilizing a lower limb resistance training intervention, another using an upper limb resistance training, and a control group. The exercise protocol involves 3 sets of 5 repetitions of resistance exercises (brachial biceps curl and leg extensions). Exercise-induced hypoalgesia will be assessed by measuring pressure pain thresholds in the thigh and elbow, comparing exercise interventions with the control group. Additionally, a secondary objective is to compare the lower limb and upper limb resistance training groups in terms of their effects on pressure pain thresholds in the thigh and elbow. Thus, the study anticipates observing differences in local and distal hypoalgesia based on the trained region.

NCT Number	NCT06765486
Lead Sponsor	Centro Universitario La Salle
Conditions	Local Hypoalgesia, Distal Hypoalgesia, Resistance Training, Pressure Pain Thresholds
Enrollment	90 participants
Start Date	2025-02-15
Primary Completion	2025-05-20 (estimated)
Study Completion	2025-06-01 (estimated)
Updated on ClinicalTrials.gov	2025-02-26