Is Negativity of Autoantibodies a Marker of Severity in Auto-immune Hepatitis?

Evaluate the proportion of seronegative auto-immune hepatitis and a possible relationship with the severity of the disease. Criteria of severity will be defined by corticodependance, corticoresistance and a severe form of the disease at diagnosis (cirrhosis or fulminant hepatitis). In case of predominant seronegative forms, other auto-antibodies related to this auto-immue hepatitis will be searched.

NCT Number	NCT06761209
Lead Sponsor	Centre Hospitalier Universitaire de la Guadeloupe
Conditions	Auto-immune Hepatitis
Enrollment	100 participants
Start Date	2022-07-01
Primary Completion	2026-12 (estimated)
Study Completion	2026-12 (estimated)
Updated on ClinicalTrials.gov	2025-01-07