Clinical Trial

Comparison of Curcumin and Intralesional Steroids in Oral Submucous Fibrosis

Not Yet Recruiting Phase 3
View on ClinicalTrials.gov →
Record status
This record was last updated March 6, 2025 (before its estimated September 2025 completion). Its status may not reflect the trial's current state.
Summary
The goal of this clinical trial is to learn if Curcumin is better than Intralesional Steroid Injection for the treatment of oral submucous fibrosis. The main question it aims to answers are: 1. If Curcumin is more effective to improve burning sensation as compared to Intralesional steroid. 2. Does Curcumin treatment results in better mouth opening versus Intralesional steroid. 3. Can Curcumin helps to improve tongue protrusion as compared to Intralesional steroids. Participants will be: * Assessed for one month, two month and three month. * Burning Sensation will be assessed with visual analogue scale (VAS). * Mouth Opening will be measured in mm with ruler. * Tongue Protrusion will be assessed with the visual analogue scale (VAS).
Protocol Amendment History 2 amendments
This ClinicalTrials.gov record has been amended 2 times since 2024-12-28; most recent amendment 2025-03-05.
Trial Details
NCT Number NCT06758739
Lead Sponsor Services Institute of Medical Sciences, Pakistan
Conditions Oral Submucous Fibrosis
Enrollment 70 participants
Start Date 2025-04
Primary Completion 2025-09 (estimated)
Study Completion 2025-10 (estimated)
Updated on ClinicalTrials.gov 2025-03-06