Clinical Trial

To Assess the Effectiveness and Safety of Catheter-based Focal Intracranial Hypothermia Combined with Endovascular Reperfusion Therapy for Patients with Acute Anterior Circulation Large Artery Occlusion

Study acronym: CHILL-ART
Recruiting
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Record status
This record was last updated January 6, 2025 (before its estimated March 30, 2026 completion). Its status may not reflect the trial's current state.
Summary
A multicenter, prospective, open-label, blinded-endpoint, randomized controlled trial to assess the effectiveness and safety of catheter-based focal intracranial hypothermia combined with endovascular reperfusion therapy for patients with acute anterior circulation large artery occlusion.
Trial Details
NCT Number NCT06758609
Lead Sponsor Guangdong Second Provincial General Hospital
Conditions Acute Cerebrovascular Accident, Acute Ischemic Stroke, Internal Carotid Artery, Middle Cerebral Artery Occlusion
Enrollment 262 participants
Start Date 2024-12-01
Primary Completion 2026-03-30 (estimated)
Study Completion 2026-06-30 (estimated)
Updated on ClinicalTrials.gov 2025-01-06