Comparison of High Flow Nasal Oxygen and Nasal Cannula in Burn Patients Under Sedation

Burn-related pain is severe and often difficult to manage. Burn patients often require high doses of opioids and anxiolytics. Anesthetic agents used during sedation such as benzodiazepines, propofol and opioids can cause respiratory depression, predisposing patients to hypoventilation and hypoxemia due to airway obstruction. Oxygen is administered to patients with a standard nasal cannula during sedation. High Flow Nasal Oxygen (HFNO) helps to improve the oxygenation of patients with respiratory distress by delivering high flow humidified oxygen through the nasal cannula at a high rate of up to 40-70 liters per minute. The aim of this study was to compare the effects of HFNO and nasal oxygen therapy in preventing hypoxemia in deeply sedated burn patients.

NCT Number	NCT06756906
Lead Sponsor	Ankara City Hospital Bilkent
Conditions	Burn Injury, Hypoxia, Sedation
Enrollment	70 participants
Start Date	2024-07-15
Primary Completion	2025-01-27 (estimated)
Study Completion	2025-02-10 (estimated)
Updated on ClinicalTrials.gov	2025-01-03